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Drug Interactions With Testosterone Topical Solution

Using testosterone topical solution with certain medications, including prednisone, cyclosporine, or insulin, can lead to drug interactions. These negative reactions can increase your risk of serious side effects or changes in blood sugar, among other problems. If drug interactions are a concern, your healthcare provider may need to adjust the dosage of your medications.

An Overview of Testosterone Topical Solution Interactions

Testosterone topical solution (Axiron®) can potentially react with several other medications. Some of the drugs that may interact with testosterone topical solution include:
 
  • Insulin
  • Corticosteroids, such as:
     
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 

More Details on Drug Interactions With Testosterone Topical Solution

The following sections explain in detail the potentially negative interactions that can occur when testosterone topical solution is combined with any of the drugs listed above.
 
Insulin
Testosterone topical solution can decrease blood sugar. If you take insulin, you should monitor your blood sugar more closely when starting or stopping testosterone topical solution, or even when adjusting your dose. You may need to adjust your insulin dose. Check with your healthcare provider for more specific instructions based on your particular situation.
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Testosterone Topical Solution Information

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