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What Is Saxagliptin Used For?

How Does Saxagliptin Work?

Saxagliptin is part of a class of diabetes medication called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones.
 
As a DPP-4 inhibitor, saxagliptin slows down the breakdown of incretin hormones, increasing the level of these hormones in the body. It is this increase in incretin hormones that is responsible for the beneficial actions of saxagliptin, including increasing insulin production in response to meals and decreasing the amount of glucose (sugar) that the liver produces.
 
Because incretin hormones are more active in response to higher blood sugar levels (and are less active in response to low blood sugar), the risk of dangerously low blood sugar (hypoglycemia) is low with saxagliptin.
 

Can Children Use Saxagliptin?

Saxagliptin is not approved for use in children. Talk with your child's healthcare provider about the benefits and risks of using saxagliptin in children.
 

Off-Label Uses

On occasion, your healthcare provider may recommend saxagliptin for something other than the treatment of type 2 diabetes. Using this medication in combination with insulin would be an example of an off-label use.
Diabetes Tips for Seniors

Saxagliptin Drug Information

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