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What Is Saxagliptin/Metformin ER Used For?

People with type 2 diabetes can use saxagliptin/metformin ER to treat this condition and keep their blood sugar levels under better control. Lifestyle changes, such as dietary modifications, are also often recommended in addition to the drug. Sometimes, it is used in combination with insulin to treat diabetes; however, this is an off-label use.

Uses for Saxagliptin/Metformin ER: An Overview

Saxagliptin/metformin ER (Kombiglyze™ XR) is a prescription medication that is used to treat type 2 diabetes. It should be used in combination with appropriate changes in diet and exercise to help control blood sugar.
Type 2 diabetes is by far the most common type (see Diabetes Types). It is also sometimes called adult-onset diabetes or noninsulin-dependent diabetes. Type 2 diabetes is a condition in which cells do not respond to insulin as well as they normally should. As a result, the cells do not take sugar out of the blood very well. This is why people with type 2 have high blood sugar.
Over time, high blood sugar can lead to a number of problems, including diabetic impotence, diabetic neuropathy, kidney failure, and heart disease (see Diabetes Complications). The cause of type 2 diabetes is not fully understood, although it is known that obesity and genetics play important roles.
Any type 2 diabetes treatment begins with lifestyle changes (weight loss, proper diet, and exercise). If lifestyle changes alone are not effective at managing diabetes, medication such as saxagliptin/metformin ER may be necessary.
Some diabetes drugs force the pancreas to produce more insulin, regardless of blood sugar levels. These medications are effective, but can cause dangerously low blood sugar (hypoglycemia). Because of the way saxagliptin/metformin ER works, it is far less likely to cause dangerously low blood sugar, compared with some other diabetes medications.
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Saxagliptin/Metformin ER Drug Information

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