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Side Effects of Saxagliptin/Metformin ER

Common Side Effects

The two individual active ingredients in saxagliptin/metformin ER -- saxagliptin and extended-release metformin -- have each been studied extensively. The specific combination (saxagliptin plus an extended-release metformin product) has not been studied.
 
However, saxagliptin/metformin ER was approved as a type 2 diabetes treatment based on the studies that combined saxagliptin plus short-acting, immediate-release metformin.
 
Based on these studies, possible common saxagliptin/metformin ER side effects might include:
 
  • Diarrhea -- in up to 9.9 percent of people
  • Upper respiratory tract infection (such as the common cold) -- up to 7.7 percent
  • Headaches -- up to 7.5 percent
  • Common cold symptoms (such as a runny nose or sore throat) -- up to 6.9 percent
  • Urinary tract infection (UTI), such as a bladder infection -- up to 6.8 percent
  • Nausea and/or vomiting -- up to 6.5 percent
  • Sinus infection and irritation -- up to 2.9 percent
  • Abdominal pain (stomach pain) -- up to 2.4 percent
  • Irritation and inflammation of the stomach and intestines (gastroenteritis) -- up to 2.3 percent.
     

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking saxagliptin/metformin ER. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
 
Steps to Prevent or Delay Diabetic Nerve Damage

Saxagliptin/Metformin ER Drug Information

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