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Drug Interactions With Saxagliptin/Metformin ER

Phenytoin
Combining saxagliptin/metformin ER with phenytoin can make saxagliptin/metformin ER less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your saxagliptin/metformin ER dose, especially when starting or stopping a phenytoin.
 
Sulfonylureas
Saxagliptin/metformin ER may increase the risk of low blood sugar due to sulfonylurea diabetes medications. Your healthcare provider may need to lower the dosage of your sulfonylurea to prevent this drug interaction from occurring.
 
Thyroid Medications
Taking saxagliptin/metformin ER with thyroid medications can make saxagliptin/metformin ER less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your saxagliptin/metformin ER dose, especially when starting or stopping a thyroid medication.
 

Final Thoughts

It is possible that not all saxagliptin/metformin ER drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
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Saxagliptin/Metformin ER Drug Information

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