The recommended starting rosiglitazone dosage is 4 mg once daily (or 2 mg twice daily). Your rosiglitazone dosing can be increased if necessary to up to 8 mg once daily (or 4 mg twice daily) after 8 to 12 weeks.
Rosiglitazone Dosage: An IntroductionThe dosage of rosiglitazone maleate (Avandia®) your healthcare provider prescribes will vary depending on a number of factors, including:
- How well your diabetes is controlled
- Other medical conditions you may have
- Other medications you may currently be taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of rosiglitazone, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take rosiglitazone.
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.
Rosiglitazone Dosage for Type 2 DiabetesThe recommended starting dosage for rosiglitazone is 4 mg once daily (or 2 mg twice daily). If necessary, your healthcare provider may increase your dosage of rosiglitazone up to 8 mg once daily (or rosiglitazone 4 mg twice daily) after 8 to 12 weeks. If you are taking insulin, the maximum recommended dosage of rosiglitazone is 4 mg once daily (or 2 mg twice daily).