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Precautions and Warnings With Rosiglitazone

There are several precautions and warnings with rosiglitazone to be aware of, including potential fluid retention, the possibility of the drug causing macular edema, and the potential risks of taking the medication while pregnant. Also, patients should be aware of possible interactions that can occur when taking this drug with other medications.

In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of rosiglitazone, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take rosiglitazone.
 
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.
 

Rosiglitazone: What Should I Tell My Healthcare Provider?

Prior to taking rosiglitazone maleate (Avandia®), you should talk with your healthcare provider if you have:
 
  • Heart problems of any kind, especially congestive heart failure (CHF)
  • Liver problems, including liver failure or cirrhosis
  • An upcoming surgery
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Have problems getting pregnant
  • Are breastfeeding
  • Are pre-menopausal without regular menstrual periods.
     
Before taking this drug, be sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
Diabetes Tips for Seniors

Rosiglitazone Maleate

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