Drug Interactions With Rosiglitazone

As with any medication, there are potential drug interactions with rosiglitazone. Taking rosiglitazone with other medications, such as seizure medications, atazanavir, and gemfibrozil, can increase or decrease the amount of rosiglitazone in your blood. As a result, some of these drug interactions can potentially increase your risk of side effects or decrease the effectiveness of rosiglitazone.

An Overview of Rosiglitazone Drug Interactions

Rosiglitazone maleate (Avandia®) can potentially interact with a few drugs. Some of the drugs that can lead to rosiglitazone interactions include:
 

 

  • Certain seizure medications, including:

 

 

 

 

  • Nitrates, such as:
     
    • Isosorbide dinitrate (BiDil®, Dilatrate® SR, Isochron™, Isordil®)
    • Isosorbide mononitrate (Imdur®, Ismo®, Monoket®)
    • Nitroglycerin tablets or capsules (NitroQuick®, Nitrostat®, Nitro-Time®)
    • Nitroglycerin ointment (Nitro-Bid®)
    • Nitroglycerin patches (Minitran®, Nitrodisc®, Nitro-Dur®, Transderm-Nitro®, Transderm-NTG®)
    • Nitroglycerin spray (Nitrolingual®)

 

  • Rifampin (Rifadin®) or rifapentine (Priftin®)

 


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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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