Rosiglitazone and Metformin

Rosiglitazone and metformin, a medication available by prescription, is used to treat type 2 diabetes in adults. It helps reduce blood sugar levels by decreasing sugar absorption into the body and improving insulin sensitivity. Rosiglitazone and metformin, which should be used in conjunction with lifestyle changes, comes in a tablet form that is usually taken once or twice a day. The combination drug is not suitable for everyone, so let your healthcare provider know if you have any heart problems, kidney problems, or liver problems.

In September 2010, the U.S. Food and Drug Administration (FDA) announced that it would be severely restricting the use of rosiglitazone due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who cannot control their diabetes on other medications (or those who are already taking the medication and doing well) will be able to take rosiglitazone.
 

What Is Rosiglitazone and Metformin?

Rosiglitazone and metformin (Avandamet®) is a prescription medication that is used to treat type 2 diabetes (also known as noninsulin-dependent diabetes or adult-onset diabetes). The drug is a combination of two different diabetes medications: rosiglitazone maleate (Avandia®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®).
 
(Click What Is Rosiglitazone and Metformin Used For? for more information on what rosiglitazone and metformin is used for, including possible off-label uses.)
 

Who Makes Rosiglitazone and Metformin?

Rosiglitazone and metformin is manufactured by GlaxoSmithKline.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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