Precautions and Warnings With Rosiglitazone and Metformin (Cont.)

Who Should Not Take Rosiglitazone and Metformin?

You should not take rosiglitazone and metformin if you:
 
  • Are allergic to rosiglitazone maleate (Avandia®), metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Fortamet®), or any inactive component used to make the combination drug. Your healthcare provider or pharmacist has a list of the inactive ingredients used to make rosiglitazone and metformin.
     
  • Have kidney disease, including kidney failure (renal failure).
     
  • Have metabolic or diabetic ketoacidosis (a life-threatening condition that may occur with uncontrolled diabetes). This condition needs to be treated with insulin.
     
  • Are seriously dehydrated (have lost a lot of water from your body).
     
  • Are going to have an x-ray procedure with injection of dyes (contrast agents).
     
  • Are going to have surgery.
     
  • Develop a serious condition, such as heart attack, severe infection, or a stroke.
     
  • Are 80 years old or older and have not had your kidney function tested.

 

Precautions and Warnings With Rosiglitazone and Metformin: Summary

There are a number of situations where rosiglitazone and metformin should not be taken, as well as a number of precautions and warnings people should be aware of before starting this drug. However, it is possible that not all the warnings or precautions for rosiglitazone and metformin were discussed in this article. Therefore, you should talk with your healthcare provider about the specific warnings or precautions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;