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Rosiglitazone and Glimepiride Dosage

The usual starting rosiglitazone and glimepiride dosage is 4 mg/1 mg once daily with the first meal of the day. However, the dosage your healthcare provider prescribes will vary depending on a number of factors, such as other medications you may be taking. Your healthcare provider may slowly increase your dosage if necessary. The maximum dose of rosiglitazone and glimepiride is 8 mg/4 mg once daily.

In September 2010, the U.S. Food and Drug Administration (FDA) announced that it was severely restricting the use of rosiglitazone and glimepiride, due to the risk of "cardiovascular events" such as heart attacks and strokes. Only individuals who could not control their diabetes on other medications (or those who were already taking the medication and doing well) would be able to take rosiglitazone and glimepiride.
However, in November 2013, the FDA announced that a careful analysis of the research suggests that there is not, in fact, any increased risk, compared to treatment with standard diabetes medications and that the use of this medication will no longer be restricted.

Rosiglitazone and Glimepiride Dosing: An Introduction

Rosiglitazone and glimepiride (Avandaryl®) is a combination of two different diabetes drugs: rosiglitazone maleate (Avandia®) and glimepiride (Amaryl®). Your healthcare provider will recommend a dosage based on a number of factors, including:
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may currently be taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
Diabetes Tips for Seniors

Rosiglitazone and Glimepiride Drug Info

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