Drug Interactions With Rosiglitazone and Glimepiride

As with any medication, there are potential drug interactions with rosiglitazone and glimepiride. Taking this drug with other medications, such as certain decongestants, some seizure medications, and oral contraceptives, can potentially lead to problems. Some of these drug interactions can increase or decrease the level of rosiglitazone and glimepiride in your blood, potentially increasing your risk of side effects or making the drug less effective.

An Overview of Rosiglitazone and Glimepiride Drug Interactions

Rosiglitazone and glimepiride (Avandaryl®) can potentially interact with several medicines. Some of the medicines that may lead to rosiglitazone and glimepiride interactions include:
 

 

 

  • Corticosteroids, such as:

 

    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®) 

 

  • Diuretics, such as:

 

 

 

 

  • Isoniazid
     
  • Niacin (nicotinic acid, Niaspan®, Niacor®, Nicolar®)

 

  • Nitrates, such as:
     
    • Isosorbide dinitrate (BiDil®, Dilatrate® SR, Isochron™, Isordil®)
    • Isosorbide mononitrate (Imdur®, Ismo®, Monoket®)
    • Nitroglycerin tablets or capsules (NitroQuick®, Nitrostat®, Nitro-Time®)
    • Nitroglycerin ointment (Nitro-Bid®)
    • Nitroglycerin patches (Minitran®, Nitrodisc®, Nitro-Dur®, Transderm-Nitro®, Transderm-NTG®)
    • Nitroglycerin spray (Nitrolingual®)

 

 

 


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(Drug Interactions With Rosiglitazone and Glimepiride Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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