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Drug Interactions With Rosiglitazone and Glimepiride

Rosiglitazone and Glimepiride Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when rosiglitazone and glimepiride are combined with any of the drugs listed above.
 
Atazanavir (Reyataz)
Taking this drug with atazanavir can increase the level of rosiglitazone and glimepiride in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of rosiglitazone and glimepiride when starting and stopping atazanavir.
 
Certain Antifungals
Taking this drug with certain antifungals can increase the level of rosiglitazone and glimepiride in your blood, increasing your risk of side effects. Your healthcare provider may need to monitor you more closely and/or adjust your dose of these medications.
 
Certain Decongestants
Taking this drug with certain decongestants can make rosiglitazone and glimepiride less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your rosiglitazone and glimepiride dose, especially when starting or stopping decongestants. Make sure you check with your healthcare provider before taking any over-the-counter cough or cold products, as these medications often contain decongestants.
 
Certain Seizure Medications
Taking this drug with certain seizure medications can decrease the level of rosiglitazone and glimepiride in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of rosiglitazone and glimepiride.
 
Corticosteroids
Taking this drug with corticosteroids can make it less effective, increasing your chance of high blood sugar (hyperglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your rosiglitazone and glimepiride dose, especially when starting or stopping a corticosteroid.
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Rosiglitazone and Glimepiride Drug Info

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