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Drug Interactions With Repaglinide

Diclofenac
Taking repaglinide and diclofenac together can increase the level of repaglinide in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your dose of repaglinide if you are taking these two medications together.
 
Gemfibrozil
If repaglinide is taken with gemfibrozil, this can greatly increase the level of repaglinide in your blood, which may increase your risk of side effects. In general, these two medications should not be taken together.
 
Monoamine Oxidase Inhibitors
Taking repaglinide with monoamine oxidase inhibitors can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your repaglinide dose, especially when starting or stopping an MAOI.
 
Montelukast
Combining repaglinide with montelukast can increase the level of repaglinide in your blood, which may increase your risk of side effects (especially dangerously low blood sugar). You healthcare provider may need to decrease your dose of repaglinide if you are taking these two medications together.
 
Nefazodone
Taking repaglinide and nefazodone together can increase the level of repaglinide in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your dose of repaglinide if you are taking these medications together.
 
Nonsteroidal Anti-Inflammatory Drugs
If repaglinide is combined with NSAIDs, this can increase your risk of low blood sugar (hypoglycemia). You may need to be monitored more closely, and your healthcare provider may need to adjust your repaglinide dose, especially when stopping or starting an NSAID, depending on your particular situation.
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Repaglinide Drug Information

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