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Repaglinide and Metformin

Clinical Studies

Hemoglobin A1c (HbA1c) is a test used to measure long-term blood sugar control. In one study, people who swtiched from metformin to repaglinide and metformin lowered their HbA1c by up to 1.4 percent on average. In the same study, people taking metformin or repaglinide alone did not lower their HbA1c as much as people taking repaglinide and metformin.
Fasting blood sugar is another way to study the effects of diabetes drugs. In studies, people who switched from metformin to repaglinide and metformin decreased their fasting blood sugar levels by 39 mg/dL on average, while people taking metformin or repaglinide alone had only small decreases (or even increases) in fasting blood sugar, on average.

When and How to Take Repaglinide and Metformin

Some general considerations include the following:
  • Repaglinide and metformin comes in tablet form. It is usually taken by mouth two or three times a day before meals.
  • It is best to take this medication 15 minutes before a meal, although you can take it up to 30 minutes before a meal if necessary. If you skip the meal, you should also skip your dose.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.

Who Makes Repaglinide and Metformin?

Repaglinide and metformin is made by Novo Nordisk, Inc.


Repaglinide and metformin tablets come in the following strengths:
  • Repaglinide and metformin 1 mg/500 mg -- 1 mg of repaglinide and 500 mg of metformin
  • Repaglinide and metformin 2 mg/500 mg -- 2 mg of repaglinide and 500 mg of metformin.
Common Symptoms of Diabetic Neuropathy

Repaglinide-Metformin Information

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