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Repaglinide and Metformin

Drug Interactions

Repaglinide and metformin can potentially interact with a number of other medications (see Drug Interactions With Repaglinide and Metformin).

What If I Take an Overdose?

An overdose may cause symptoms that include, but are not limited to:
If you happen to overdose on repaglinide and metformin, seek immediate medical attention.
(Click PrandiMet Overdose for more information.)

What Should I Do If I Miss a Dose?

If you do not take your dose as scheduled, simply skip the missed dose and continue with your regular schedule. Do not take a double dose of the medication. Remember that this medication must be taken before meals; do not take it at any other time.

Generic Availability

This medication is not available in generic form.
(Click Generic PrandiMet for more information.)

How Does It Work?

Repaglinide and metformin contains two different diabetes medicines. These two medications work differently and have the following effects in the body:
  • Repaglinide belongs to a group of diabetes medications called meglitinides. Meglitinides can lower blood sugar by helping the pancreas make more insulin. Another type of diabetes medication known as sulfonylureas (see PrandiMet Alternatives) also helps the pancreas make more insulin. However, unlike sulfonylureas, repaglinide is a short-acting medication and is generally used to lower blood sugar levels after meals.
  • Metformin works in several ways. It decreases the amount of sugar (glucose) made by the liver. This medication can also decrease the amount of sugar absorbed into the body (from the diet) and can make insulin receptors more sensitive, improving the way the body responds to its own insulin. All of these effects cause a decrease in blood sugar levels.
7 Signs of High Blood Sugar

Repaglinide-Metformin Information

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