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Drug Interactions With Repaglinide and Metformin

If certain medications are combined with repaglinide and metformin, it could cause serious complications. Some of the medications that could cause negative drug interactions with repaglinide and metformin include certain antibiotics, protease inhibitors, and digoxin. Some of these interactions may alter the amount of the medications in your blood. To avoid complications, your healthcare provider may monitor you more closely or adjust your dosages as necessary.

An Overview of Drug Interactions With Repaglinide and Metformin

Repaglinide and metformin (PrandiMet™) can potentially interact with several other medications. Some of these medicines that may lead to repaglinide and metformin drug interactions include:


    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Posaconazole (Noxafil®)
    • Telithromycin (Ketek®)
    • Trimethoprim (Primsol®) or trimethoprim/sulfamethoxazole (Bactrim™, Septra®)
    • Voriconazole (VFEND®)
    • Vancomycin (Vancocin®)




  • Trimethoprim or combination drugs that contain trimethoprim (Bactrim®, Bactrim® DS, Septra®, Septra® DS, Sulfatrim®).


Diabetes Tips for Seniors

Repaglinide-Metformin Information

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