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Propylthiouracil Side Effects

Most people do not experience side effects with propylthiouracil; however, serious reactions to the drug are possible, including liver damage, inflammation of the kidneys, and allergic reactions. As a result, propylthiouracil has largely been replaced by newer medications that are less likely to cause side effects. If you experience an adverse reaction to this drug, notify your healthcare provider.

An Introduction to Propylthiouracil Side Effects

As with any medicine, side effects are possible with propylthiouracil (PTU). Although not everyone who takes the medication will experience problems, serious reactions can occur. In fact, propylthiouracil is rarely used anymore, since other treatments are less likely to cause dangerous side effects.
(This article covers many, but not all, of the possible side effects with this medication. Your healthcare provider can discuss a more complete list with you.)

Possible Side Effects of Propylthiouracil

Propylthiouracil is a relatively old medication, approved before it was standard practice to include highly detailed side effect information in the prescribing information for medications. As a result, only vague side effect information is available, with no percentages.
Based on this limited information, some of the possible propylthiouracil side effects include but are not limited to:
  • Nausea
  • Vomiting
  • Heartburn or indigestion
  • Joint pain
  • Loss of taste
  • Drowsiness
  • Taste changes
  • Headache
  • A spinning sensation (vertigo)
  • Skin pigmentation changes
  • Inflammation of lymph nodes or salivary glands.
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Propylthiouracil Medication Information

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