Endocrine System Channel
Topics
Medications
Quicklinks
Related Channels

Prolactinoma Treatment

Bromocriptine
Bromocriptine is associated with side effects such as nausea and dizziness. To avoid these side effects, it is important to begin treatment with bromocriptine slowly. An example of a typical approach used by an experienced endocrinologist is as follows:
 
Begin by taking a quarter of a 2.5-milligram tablet of bromocriptine with a snack at bedtime. After three days, increase the dose to a quarter of a tablet with breakfast and a quarter at bedtime. After three more days, take half a tablet twice a day, and three days later, take one tablet at night and half with breakfast. Finally, the dose is increased to one tablet twice a day.
 
If the prolactin level is still high, add half a tablet with lunch. If the medication is well tolerated, increase the dose to a full tablet. If side effects develop with a higher dose, return to the previous dosage. With time, side effects will disappear while the drug continues to lower prolactin.
 
Treatment with bromocriptine should not be interrupted without consulting a qualified endocrinologist. Prolactin levels often rise again in most people when the drug is discontinued. In some patients, however, prolactin levels remain normal, so the doctor may suggest reducing or discontinuing treatment every two years on a trial basis.
 
Cabergoline
Cabergoline is also associated with side effects such as nausea and dizziness, but these may be less common and less severe than with bromocriptine. As with bromocriptine therapy, side effects may be avoided if this treatment method is started slowly. An example of a typical approach used by an experienced endocrinologist is as follows:
 
Begin by taking 0.25 milligrams (or half a tablet) twice a week. After four weeks, increase the dose by 0.25 milligrams to 0.50 milligrams (or 1 tablet) twice a week. After four more weeks, increase the dose by 0.25 milligrams to 0.75 milligrams (or 1.5 tablets) twice a week. Finally, after four additional weeks, the dose can be increased to 1 milligram (or 2 tablets) twice a week.
 
If side effects develop with a higher dose, the doctor may return to the previous dosage. If a patient's prolactin level remains normal for six months, a doctor may consider stopping prolactinoma treatment.
 
Cabergoline treatment should not be interrupted without consulting a qualified endocrinologist.
 
7 Signs of High Blood Sugar

Prolactinoma Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.