There is no evidence suggesting a link between prolactinoma and birth control pills. In addition, patients with prolactinomas can undergo estrogen replacement therapy after menopause.
At one time, birth control pills were thought to contribute to the development of prolactinomas; however, this is no longer thought to be true. Patients with prolactinomas who are treated with bromocriptine or cabergoline may also take oral contraceptives.
Similarly, post-menopausal estrogen replacement therapy is safe for patients during prolactinoma treatment with medicines or following surgery.