Pramlintide (Cont.)

Overdose With Pramlintide

People who take too much pramlintide may have overdose symptoms that could include:
 
  • Severe nausea
  • Vomiting
  • Diarrhea
  • Dizziness.
     
If you happen to overdose on pramlintide, seek medical attention immediately.
 
(Click Symlin Overdose for more information.)
 

Pramlintide Storage Methods

Unopened pramlintide vials and pens should be stored in the refrigerator. Pramlintide should not be frozen, and you should not use any pramlintide that has been frozen. Once you have opened a pramlintide vial or pen, it can be stored in the refrigerator or at room temperature (up to 86°F). If your room temperature is above 86°F, you should store pramlintide in the refrigerator. Once a pramlintide vial or pen is opened, you must throw it away after 30 days (four weeks), whether it was stored in the refrigerator or not.
 
Keep pramlintide and all medications out of the reach of children.
 

Pramlintide: What Should I Do If I Miss a Dose?

If you do not take pramlintide as scheduled, skip your missed dose and continue with your regular schedule. If you skip a meal, you should also skip your pramlintide dose.
 

Pramlintide Strengths

Pramlintide is available in 5-mL vials containing pramlintide 600 mcg per mL. Pramlintide also comes in pen form, available in the following strengths:
 
  • SymlinPen 60 (which can inject doses of 15, 30, 45, and 60 mcg of Symlin)
  • SymlinPen 120 (which can inject doses of 60 or 120 mg of Symlin).
     
You will need to purchase pen needles (which do not come with the pramlintide pens), in order to use the pens. Make sure your healthcare provider gives you a prescription for pen needles.
 
(Pramlintide Continued: Page 6)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;