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Pramlintide Dosage

Generally, the recommended starting pramlintide dosage for treating type 1 diabetes is 15 mcg right before major meals. It may then be increased in 15 mcg increments (up to a maximum of 60 mcg) if it does not cause nausea for at least three days. For treating type 2 diabetes, the usual starting pramlintide dosage is 60 mcg right before meals; the dose may be increased to 120 mcg after the patient has had no nausea for at least three to seven days.

Pramlintide Dosage: An Introduction

The dose of pramlintide acetate (Symlin®) your healthcare provider prescribes will vary depending on a number of factors, including:
 
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Pramlintide Dosage for Type 1 Diabetes

The starting dose of pramlintide for people with type 1 diabetes is 15 mcg right before major meals. Your healthcare provider will need to adjust the dose of your insulin (see the "Insulin Adjustment With Pramlintide" section of this article). Your healthcare provider may increase your dose of pramlintide by 15 mcg increments (up to a maximum of 60 mcg) after at least three days without nausea. If nausea does not go away with 45 mcg or 60 mcg doses, the dose can be reduced to 30 mcg. If nausea does not go away at the 30 mcg dose, your healthcare provider may want to consider stopping pramlintide altogether. Do not adjust your pramlintide dose unless your healthcare provider specifically instructs you to do so.
 

Pramlintide Dosage for Type 2 Diabetes

The starting dose of pramlintide for people with type 2 diabetes is 60 mcg right before major meals. Your healthcare provider will need to adjust the dose of your insulin (see the following section). Your healthcare provider may increase your pramlintide dose to 120 mcg before major meals after you have experienced no nausea for at least three to seven days. If nausea does not go away at the 120 mcg dose, the dose can be decreased to 60 mcg. Do not adjust your pramlintide dose unless your healthcare provider specifically instructs you to do so.
 
Steps to Prevent or Delay Diabetic Nerve Damage

Pramlintide (Symlin)

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