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Pituitary Tumor Symptoms

ACTH-Producing Tumors

When a pituitary tumor secretes ACTH (also known as Cushing's disease), a variety of symptoms can occur. Some of the pituitary tumor symptoms seen with high levels of ACTH include:
  • Extreme weight gain, especially around the midsection and upper back
  • Excess hair growth
  • Purplish-pink stretch marks on the abdomen, thighs, buttocks, arms, and breasts
  • Acne
  • High blood pressure
  • Skin problems
  • Growth retardation
  • Either very early or late puberty
  • Sleep disturbances
  • Muscle weakness
  • Menstrual disorders in women
  • Osteoporosis
  • Moodiness, irritability, or depression
  • Diabetes
  • Decreased fertility in men
  • Diminished or absent desire for sex.
(Click Symptoms of Cushing's Disease for more information about symptoms caused by this type of pituitary tumor.)

Thyroid Hormone-Producing Tumors

Some pituitary tumors can disrupt the function of the thyroid gland by secreting thyroid-stimulating hormone (TSH). This, in turn, enlarges the thyroid, causing a visibly large lump in the neck known as a goiter. These tumors may also produce other symptoms, including:
  • Nervousness
  • Rapid pulse
  • Weight loss
  • Excessive eating
  • Sweating
  • Frequent bowel movements
  • Sensitivity to heat.
Pituitary tumors that limit the secretion of TSH can also affect a person in many ways, including problems with concentration, tiredness, constipation, dry skin, and sensitivity to cold. They may also cause girls to have irregular periods or not to menstruate at all.
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Pituitary Tumors

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