Pioglitazone and Metformin (Cont.)

Drug Interactions With Pioglitazone and Metformin

Pioglitazone and metformin can interact with a number of medicines (see Drug Interactions With Pioglitazone and Metformin).
 

Pioglitazone and Metformin: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking pioglitazone and metformin if you have:
 
  • Heart problems of any kind, especially congestive heart failure (CHF)
  • A history of heart attack or stroke
  • Liver problems, including liver failure or cirrhosis
  • Low vitamin B12 levels (pernicious anemia)
  • Kidney problems, including kidney failure (renal failure)
  • An upcoming surgery or procedure (including x-rays and other radiology procedures)
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant (see Actoplus Met and Pregnancy)
  • Are breastfeeding
  • Are having problems getting pregnant
  • Are premenopausal without regular menstrual periods
  • Drink alcohol.
     
Tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Pioglitazone and Metformin to learn more, including information on who should not take the drug.)
 
(Pioglitazone and Metformin Continued: Page 5)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;