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Pioglitazone and Metformin Dosing

Pioglitazone and Metformin Dosing for People Switching From Actos

If you are switching to pioglitazone and metformin from just pioglitazone (Actos), the recommended starting dose is pioglitazone and metformin 15 mg/500mg twice daily or 15 mg/850 mg once daily. If necessary, your healthcare provider may gradually increase your pioglitazone and metformin dose up to 45 mg/2550 mg total per day. Slowly increasing the dose helps to prevent stomach upset, which may be caused by the metformin component of the drug.

General Information on Pioglitazone and Metformin Dosing

Some considerations for people taking pioglitazone and metformin include the following:
  • It is best to try to take pioglitazone and metformin with food in order to avoid stomach upset.
  • Pioglitazone and metformin should be taken at the same time(s) each day to maintain an even level of the medication in your blood.
  • If you do not take your pioglitazone and metformin as scheduled, take your next dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue as scheduled. Do not take a double dose of pioglitazone and metformin.
  • For pioglitazone and metformin to work properly, you have to take it as prescribed. The medication will not work if you take it differently than how your healthcare provider recommends.
  • If you are unsure about anything related to pioglitazone and metformin or pioglitazone and metformin dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking pioglitazone and metformin without first discussing it with your healthcare provider.
Healthy Eating for People With Diabetes

Pioglitazone and Metformin (Actoplus Met)

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