Pioglitazone and Glimepiride (Cont.)

Alternatives to Pioglitazone and Glimepiride

In general, type 2 diabetes treatment begins with lifestyle changes (for example, weight loss, exercise, and diet). If lifestyle changes alone are not effective at managing diabetes, medication (such as pioglitazone and glimepiride) may be necessary.
 
The main goal of diabetes medicine is to lower blood sugar levels enough to reduce your risk of developing problems related to diabetes, such as heart, nerve, eye, or kidney problems. Because pioglitazone and glimepiride can lower blood sugar levels, people may also be able to lower their risk for developing problems related to high blood sugar.
 
For most people, pioglitazone and glimepiride is quite effective at controlling blood sugar. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, you may need to combine pioglitazone and glimepiride with another diabetes medicine, such as metformin (Glucophage®) or insulin. You may also wish to consider a substitute for pioglitazone and glimepiride. These substitutes could include other combination medications or a different type of diabetes medication.
 
(Click Duetact Alternatives to learn more.)
 
To learn about controlling diabetes through lifestyle choices, click any of the following eMedTV links:
 

What If I Take an Overdose of Pioglitazone and Glimepiride?

People who take too much pioglitazone and glimepiride may have overdose symptoms that include:
 
  • Low blood sugar (hypoglycemia)
  • Fainting
  • Shakiness
  • Fast heartbeat (tachycardia)
  • Confusion
  • Sweating.
     
If you happen to overdose on pioglitazone and glimepiride, seek immediate medical attention.
 
(Click Duetact Overdose for more information.)
 
(Pioglitazone and Glimepiride Continued: Page 6)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;