NPH Insulin/Regular Insulin

NPH insulin/regular insulin is an over-the-counter medication used for controlling blood sugar in people with diabetes. It is a combination product that contains an intermediate-acting insulin and a short-acting insulin. This diabetes medication is injected just under the skin, about half an hour before meals. Potential side effects include low blood sugar, allergic reactions, and skin reactions at the injection site.

What Is NPH Insulin/Regular Insulin?

NPH insulin/regular insulin is a non-prescription insulin medication. It is sold under the brand names Humulin® 70/30, and Novolin® 70/30. Like other forms of insulin, NPH insulin/regular insulin is used to help control blood sugar in people with diabetes. It contains a mixture of two different types of insulin: a short-acting insulin (regular insulin) and an intermediate-acting insulin (NPH insulin).
 
(Click What Is NPH Insulin/Regular Insulin Used For? for more information, including possible off-label uses.)
 

Potential Side Effects

As with any medicine, side effects are possible with NPH insulin/regular insulin. These side effects can be quite dangerous, especially if the dose is too high.
 
Possible side effects of NPH insulin/regular insulin (as well as with all other forms of insulin) include but are not limited to:
 
  • Low blood sugar levels (hypoglycemia)
  • A skin reaction at the injection site
  • Thickening or pitting of the skin at the injection site
  • Allergic reactions.
     
(Click Side Effects of NPH Insulin/Regular Insulin to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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