NovoLog Mix 70/30 Drug Interactions

There are a number of medications that may interact with NovoLog Mix 70/30. Drug interactions could occur if the insulin is combined with oral diabetes medicines, ACE inhibitors, beta blockers, or sulfonamide antibiotics. Drug interactions with NovoLog Mix 70/30 may result in dangerously low blood sugar levels, so be sure to tell your healthcare provider any time you start, stop, or change the dose of any medication.

NovoLog Mix 70/30 Drug Interactions: An Overview

NovoLog® Mix 70/30 (insulin aspart protamine/insulin aspart) can potentially interact with several medications, too many to list entirely in this article. Some interactions (which are not discussed in this article) may increase blood sugar levels. While this is not healthy, it is usually not dangerous right away. Other NovoLog Mix 70/30 drug interactions can result in dangerously low blood sugar levels (known medically as hypoglycemia). Some of the medicines that may cause dangerously low blood sugar when combined with NovoLog Mix 70/30 include:
 
  • Angiotensin-converting enzyme inhibitors (ACE inhibitors), such as:

 

 

 

 

 

 

  • Monoamine oxidase inhibitors (MAOIs), such as:

 

 

 

    • Aspirin (Ecotrin®, Bayer®, Anacin®)
    • Choline magnesium trisalicylate (Trilisate®)
    • Diflunisal (Dolobid®)
    • Salsalate (Salflex®, Disalcid®, Amigesic®)

 

  • Sulfonamide antibiotics ("sulfa drugs"), such as:

 

    • Sulfadiazine
    • Sulfadoxine (Fansidar®)
    • Sulfamethoxazole (Bactrim®, Septra®)
    • Sulfisoxazole (Gantrisin®).

 


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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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