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Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking nateglinide if you have:
  • Kidney problems, including kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • An upcoming surgery
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Nateglinide to learn more, including information on who should not take the drug.)

Alternatives to Nateglinide

In general, treatment for type 2 diabetes begins with lifestyle changes (for example, weight loss, exercise, and diet). If lifestyle changes alone are not effective in managing diabetes, medication such as nateglinide may be necessary.
The main goal of diabetes medication is to lower blood sugar levels enough to reduce the risk of developing problems related to the condition, such as heart, nerve, eye, or kidney problems. Because nateglinide can lower blood sugar levels, people may be able to lower their risk for developing problems related to high blood sugar by taking it.
Nateglinide is quite effective in controlling blood sugar. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, nateglinide may need to be combined with another diabetes medicine, such as metformin (Glucophage®) or insulin. You may also wish to consider a substitute for nateglinide. These could include another meglitinide or other diabetes drugs, either by themselves or in combination.
(To learn about controlling diabetes through lifestyle choices, click the following eMedTV links:
Steps to Prevent or Delay Diabetic Nerve Damage

Nateglinide for Diabetes

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