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Metoclopramide Side Effects

Headaches, nausea, insomnia, and dizziness are some of the side effects that may occur with metoclopramide. Side effects of the medication are mild in most cases and either do not require medical attention or can be treated easily. Some side effects of metoclopramide are potentially serious, however, and should be reported to your healthcare provider immediately, including vision changes, frequent infections, or a high fever.

An Introduction to Metoclopramide Side Effects

As with any medicine, side effects are possible with metoclopramide (Reglan®). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with metoclopramide. Your healthcare provider can discuss a more complete list of metoclopramide side effects with you.)
 

Side Effects With Metoclopramide to Report

There are a number of possible metoclopramide side effects that you should report immediately to your healthcare provider, including, but not limited to:
 

 

    • Unusual body, facial, or tongue movements
    • Muscle tension or contractions
    • Feelings of internal restlessness or jitteriness

 

  • Signs or symptoms of neuroleptic malignant syndrome, which can include:

 

    • A high fever
    • Stiff muscles
    • Confusion
    • Irregular pulse or blood pressure
    • An increased heart rate (tachycardia)
    • Sweating
    • Irregular heart rhythms (arrhythmias)

 

 

 

  • High blood pressure (hypertension) or low blood pressure (hypotension)
  • A rapid heart rate (tachycardia) or a slow heart rate (bradycardia)
  • Signs of congestive heart failure (CHF), such as fluid retention and shortness of breath
  • Signs of liver problems, such as yellow eyes or skin (jaundice) or high liver enzymes (found using a blood test)
  • Any vision changes (metoclopramide can cause severe and permanent eye damage)
  • Blue discoloration of the skin, especially if accompanied by shortness of breath
  • Frequent or severe infections
  • Signs of an allergic reaction, such as:

 

    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling (especially of the lips, mouth, or throat)
    • Wheezing or other breathing problems.

 

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