Drug Interactions With Metoclopramide

A number of medications may cause drug interactions with metoclopramide, including diabetes medicines, cyclosporine, monoamine oxidase inhibitors (MAOIs), and antipsychotics. These interactions could increase your risk for developing side effects or decrease the effectiveness of the medications. To help prevent negative metoclopramide interactions, be sure to let your healthcare provider know if you are taking any other medications.

Metoclopramide HCl Drug Information

An Overview of Metoclopramide Drug Interactions

Metoclopramide (Reglan^®) can potentially interact with a few other medications. Some of these medicines that may lead to metoclopramide interactions include:

Antipsychotics
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Diabetes medications
Digoxin (Digitek^®, Lanoxin^®)
Monoamine oxidase inhibitors (MAOIs), including:

Isocarboxazid (Marplan^®)
Phenelzine (Nardil^®)
Rasagiline (Azilect^®)
Selegiline (Eldepryl^®, Emsam^®, Zelapar^®)
Tranylcypromine (Parnate^®)

Other medications or substances that cause drowsiness, such as alcohol, narcotics, sleep medications, or anxiety medications
Parkinson's disease medications
Seizure medications.

Metoclopramide Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when metoclopramide is combined with any of the drugs listed above.

(Drug Interactions With Metoclopramide Continued: Page 2)