Endocrine System Home > Tirosint

Tirosint is a prescription drug approved for treating an underactive thyroid and certain other thyroid problems. Specifically, this medication works by increasing the body's level of thyroid hormones. It comes in the form of a soft-gelatin capsule and is taken once daily in the morning. Potential side effects may include hair loss, insomnia, and heart palpitations.

What Is Tirosint?

Tirosint® (levothyroxine sodium) is a prescription medication that is a manufactured version of a certain thyroid hormone. Even though it is synthetic, the drug is identical to the naturally occurring hormone levothyroxine (also known as T4). Tirosint is used to treat an underactive thyroid (known medically as hypothyroidism), as well as various other thyroid problems (including certain types of thyroid cancer).
Tirosint is uniquely formulated in soft-gelatin capsules. It has been suggested that this formulation may provide a more consistent and stable dosage, compared to other levothyroxine formulations.
(Click Tirosint Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Tirosint is made by IBSA Institut Biochimique SA for Akrimax Pharmaceuticals, LLC.

How Does Tirosint Work?

The thyroid gland makes two different thyroid hormones -- levothyroxine (T4) and triiodothyronine (T3). Typically, the thyroid produces much more T4 than T3 (however, T3 is much more active than T4). The body can convert the T4 hormone into T3 as necessary. If your thyroid does not make enough thyroid hormones, there are a few different ways to increase your levels.
Some forms of thyroid replacement therapy combine T4 and T3 (such as natural thyroid replacement made from pig thyroids). However, because the body converts T4 into T3 as needed, most people can successfully take just T4 (such as with Tirosint). Alternatively, just T3 can be taken (as products such as Cytomel®). Currently, most people take just T4 (such as Tirosint).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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