Endocrine System Home > Rosiglitazone

When and How to Take Rosiglitazone

Some general considerations for when and how to take rosiglitazone include:
  • The medication comes in tablet form. It should be taken by mouth once or twice daily.
  • You can take it with or without food. If the medicine bothers your stomach, try taking it with food.
  • It should be taken at the same time(s) each day to maintain an even level of the drug in your blood.
  • For rosiglitazone to work properly, it must be taken as prescribed. It will not work if you stop taking it.

Dosing Information

The dose of rosiglitazone your healthcare provider recommends will vary depending on a number of factors, including:
  • How well your diabetes is controlled
  • Other medical conditions you may have
  • Other medications you may currently be taking.
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Rosiglitazone Dosing for more information.)

Drug Interactions

Rosiglitazone can potentially interact with a number of medicines.
(Click Drug Interactions With Rosiglitazone for more information.)

Alternatives to Rosiglitazone

In general, type 2 diabetes treatment begins with lifestyle changes. If lifestyle changes are not effective at managing diabetes, medication (such as rosiglitazone) may be necessary.
The main goal of diabetes medicine is to lower blood sugar levels enough to reduce your risk of developing problems related to diabetes, such as heart, nerve, eye, or kidney problems. Because rosiglitazone can lower blood sugar levels, people may be able to lower their risk for developing problems related to high blood sugar.
For most people, rosiglitazone is quite effective at controlling blood sugar. It is also generally well tolerated. However, side effects can occur -- or the medicine may not work as well as needed. In these cases, you may need to combine rosiglitazone with another diabetes medicine, such as metformin (Glucophage®) or insulin. You may also wish to consider a substitute for rosiglitazone. These substitutes could include other thiazolidinediones or other diabetes medicines, either by themselves or in combination.
(Click Avandia Alternatives to learn more about alternatives to this medication. To learn about controlling diabetes through lifestyle choices, click on the links below:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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