Endocrine System Home > What Is Rosiglitazone and Metformin Used For?

Rosiglitazone and Metformin as Part of Diabetes Treatment

The main goal of any diabetes treatment is to lower your blood sugar levels (as measured by your hemoglobin A1c [HbA1c]) enough to reduce your risk for developing problems related to diabetes (see Diabetes Complications).
Any type 2 diabetes treatment begins with lifestyle changes. If lifestyle changes are not effective at managing diabetes, diabetes medication (such as rosiglitazone and metformin) may be necessary. Some diabetes drugs force the pancreas to produce more insulin (see Avandamet Alternatives). These medications are effective but can cause dangerously low blood sugar (hypoglycemia). Because rosiglitazone and metformin does not force the pancreas to make more insulin, the risk of dangerously low blood sugar is low with rosiglitazone and metformin (see Avandamet and Blood Sugar).
To learn about controlling diabetes through lifestyle choices, click on any of the eMedTV links below:

Is Rosiglitazone and Metformin Used for Diabetes Treatment in Children?

Rosiglitazone and metformin has not been adequately studied in children, and there is not enough information available to recommend the use of this drug in children. Talk to your healthcare provider about the benefits and risks of using this drug in children.

Is Rosiglitazone and Metformin Used Off-Label?

On occasion, your healthcare provider may recommend rosiglitazone and metformin for treating something other than diabetes. This is called an "off-label" use. At this time, the treatment of polycystic ovarian syndrome (PCOS) is an off-label use of this drug.
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Last reviewed by: Kristi Monson, PharmD;
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