Endocrine System Home > Repaglinide

Drug Interactions With Repaglinide

Repaglinide can potentially interact with a number of medicines (see Drug Interactions With Repaglinide).

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking repaglinide if you have:
  • Kidney problems, including kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Adrenal insufficiency or adrenal fatigue
  • Pituitary gland problems
  • An upcoming surgery
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also let your healthcare provider know if you are:
Tell your healthcare provider about all other medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Repaglinide to learn more, including information on who should not take the drug.)

Alternatives to This Medicine

In general, treatment for type 2 diabetes begins with lifestyle changes (for example, weight loss, exercise, and diet). If lifestyle changes alone are not effective in managing diabetes, medication such as repaglinide may be necessary.
The main goal of diabetes drugs is to lower blood sugar levels enough to reduce your risk of developing problems related to diabetes, such as heart, nerve, eye, or kidney problems. Because repaglinide can lower blood sugar levels, people may be able to lower their risk of developing problems related to high blood sugar by taking it.
Repaglinide is typically quite effective in controlling blood sugar. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, it may need to be combined with another diabetes medicine, such as metformin (Glucophage®) or insulin.
You may also wish to consider a substitute for repaglinide. These can include another meglitinide or diabetes drug, either by itself or in combination.
(Click Prandin Alternatives to learn more.)

To learn about controlling diabetes through lifestyle choices, click the following eMedTV links:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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