Endocrine System Home > Repaglinide and Metformin

Repaglinide and metformin is used to help lower blood sugar levels in people with type 2 diabetes. It works in several ways, such as helping the pancreas to make more insulin, improving the body's response to insulin, and decreasing the amount of sugar produced by the liver. This prescription medication, which comes in tablet form, is typically taken up to half an hour before each meal. Potential side effects include headaches, nausea, and diarrhea.

What Is Repaglinide and Metformin?

Repaglinide and metformin (PrandiMet™) is a prescription medication approved to treat type 2 diabetes. It is a combination of two different diabetes medications: repaglinide (Prandin®) and metformin hydrochloride (Fortamet®, Glucophage®, Glucophage XR®, Glumetza®, or Riomet®).
 
(Click What Is Repaglinide and Metformin Used For? for more information, including possible off-label uses.)
 

Side Effects of Repaglinide and Metformin

As with any medicine, side effects are possible. However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. As with most diabetes medications, low blood sugar is a potentially serious side effect of repaglinide and metformin.
 
Some of the most common side effects include, but are not limited to:
 
(Click Side Effects of Repaglinide and Metformin to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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