Endocrine System Home > Propylthiouracil Side Effects

Side Effects to Report

Some side effects with propylthiouracil are potentially serious -- even life-threatening -- and should be reported to your healthcare provider. These include but are not limited to:
 
  • Signs of low white blood cells, such as:
     
 
  • Signs of anemia, such as pale skin and fatigue
  • Signs of low blood platelets, such as easy bruising or bleeding
  • Signs of inflammation of the blood vessels (vasculitis), such as:
     
    • Weight loss
    • Fatigue
    • Muscle and joint aches
    • Abdominal pain (stomach pain)
    • Difficulty breathing
    • Skin ulcers
    • Fever
 
  • Signs of kidney inflammation (nephritis), such as water retention and decreased urination
  • Signs of liver damage, such as:
     
    • Yellowing of the skin or the whites of the eyes (jaundice)
    • Upper-right abdominal pain
    • Loss of appetite
    • Itching
    • High liver enzymes (found using a blood test)
 
  • Signs of an allergic reaction, including:
     
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 

Final Thoughts

You may experience some or none of the propylthiouracil side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
 
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking this drug. Also, let your healthcare provider know if you develop something that "just does not seem right." While it may not be related to propylthiouracil, your healthcare provider will be able to diagnose and treat the problem.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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