The main goal of diabetes medicine is to lower blood sugar levels enough to reduce your risk of developing problems related to diabetes, such as heart, nerve, eye, or kidney problems. Because pioglitazone and glimepiride can lower blood sugar levels, people may also be able to lower their risk for developing problems related to high blood sugar.
For most people, pioglitazone and glimepiride is quite effective at controlling blood sugar. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, you may need to combine pioglitazone and glimepiride with another diabetes medicine, such as metformin (Glucophage®) or insulin. You may also wish to consider a substitute for pioglitazone and glimepiride. These substitutes could include other combination medications or a different type of diabetes medication.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 6, 2013.
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