Endocrine System Home > Methimazole

Methimazole is an antithyroid medication that can help bring high thyroid levels under control. It works to disrupt the production of thyroid hormone by preventing the oxidation of iodine. Typically taken three times a day, this drug comes in the form of a tablet that can be taken with or without food. Some of the medication's possible side effects include muscle pain, nausea, and vomiting.

What Is Methimazole?

Methimazole (Tapazole®) is a prescription antithyroid medication used to treat an overactive thyroid (known medically as hyperthyroidism).
(Click What Is Methimazole Used For? for more information, including possible off-label uses.)

Are There Side Effects?

As with any medicine, side effects are possible with methimazole. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider. Serious reactions are less common.
Some of the possible methimazole side effects include but are not limited to:
  • Nausea
  • Vomiting
  • Hair loss
  • Headache
  • Muscle pain.
(Click Side Effects of Methimazole to learn more, including potentially serious reactions you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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