Endocrine System Home > Linagliptin/Metformin

Available as a prescription medicine, linagliptin/metformin is used in the treatment of type 2 diabetes. This combination medication works in a variety of ways, such as improving insulin production and decreasing the amount of glucose produced by the liver. Possible side effects may include diarrhea and symptoms similar to the common cold. It comes as a tablet that is taken twice daily.

What Is Linagliptin/Metformin?

Linagliptin/metformin (Jentadueto™) is a prescription diabetes medication approved to treat type 2 diabetes in adults. It contains a combination of linagliptin (Tradjenta™) and metformin (Glucophage®).
(Click What Is Linagliptin/Metformin Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, linagliptin/metformin may cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects of linagliptin/metformin include but are not limited to:
(Click Linagliptin/Metformin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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