Endocrine System Home > Levothyroxine Overdose

Taking even a little too much levothyroxine can cause an overdose on the medication. A levothyroxine overdose can cause dangerous symptoms, such as confusion, seizures, or strokes. The effects from a levothyroxine overdose will vary depending on how much of the medication was taken and whether it was taken with other substances.

Levothyroxine Overdose: An Introduction

Levothyroxine sodium is a prescription medication that is a synthetic version of a naturally occurring thyroid hormone. Taking too much levothyroxine can result in a condition known as hyperthyroidism, which can be quite dangerous.
The specific effects of a levothyroxine overdose will vary depending on a number of factors, including the levothyroxine dosage and whether it was taken with any other medications or substances.

Symptoms of a Levothyroxine Overdose

Levothyroxine is a "narrow therapeutic index" drug, which means that the safe and effective dose is usually very close to the toxic dose. Therefore, an overdose can result from taking just a little too much levothyroxine. The symptoms of a levothyroxine overdose can be very dangerous. Some of the most dangerous symptoms include:

Treatment for a Levothyroxine Overdose

The treatment for a levothyroxine overdose will also vary. If the overdose was recent, the healthcare provider may administer certain medicines or place a tube into the stomach to "pump the stomach." Treatment also involves supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options may include:
  • Fluids through an intravenous line (IV), if necessary
  • Medications to control high blood pressure, arrhythmias, seizures, or other symptoms
  • Other treatments based on the complications that occur.
It is important that you seek medical attention immediately if you believe that you may have overdosed on levothyroxine.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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