Endocrine System Home > Side Effects of Insulin Glulisine

In clinical trials of insulin glulisine, side effects that were commonly reported included low blood sugar levels and skin reactions at the injection site. While most people tolerate this medication well, serious side effects can also occur that need immediate medical attention. Notify your healthcare provider right away if you develop serious side effects of insulin glulisine, such as blurred vision, difficulty speaking, or allergic reactions.

An Introduction to Side Effects of Insulin Glulisine

As with any medicine, side effects are possible with insulin glulisine (Apidra®). However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, they are often minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with insulin glulisine. Your healthcare provider can discuss a more complete list of insulin glulisine side effects with you.)
 

Serious Insulin Glulisine Side Effects: Warning Signs

Some side effects of insulin glulisine are potentially serious and should be reported immediately to your healthcare provider. Warning signs of these serious side effects include:
 
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing
 
  • Symptoms of low blood sugar, such as:
 
    • Cold sweats
    • Shakiness
    • Sweating
    • Dizziness
    • Extreme hunger
    • Blurry vision
    • Changes in behavior, such as irritability
    • Loss of coordination
    • Difficulty speaking
    • Confusion
    • Seizures
    • Unconsciousness.
 
Some people may have different signs of low blood sugar. Make sure those around you know how to recognize your particular signs, as you may be too confused, due to low blood sugar, to recognize and adequately respond to low blood sugar levels.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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