Endocrine System Home > Humalog Mix75/25

Humalog Mix75/25 is a medication approved to control blood sugar levels in people who have diabetes. This prescription medication starts working quickly and continues to work for several hours, as it contains both an intermediate-acting and a rapid-acting insulin. Humalog Mix75/25 is typically injected just under the skin twice a day. Possible side effects include allergic reactions and reactions at the injection site.

What Is Humalog Mix75/25?

Humalog® Mix75/25 (insulin lispro protamine/insulin lispro) is a prescription insulin medication. Like all forms of insulin, it is used to treat diabetes. It contains a mixture of two different types of insulin: insulin lispro protamine (an intermediate-acting insulin) and insulin lispro (a rapid-acting insulin). Ideally, using Humalog Mix75/25 decreases the number of injections per day, as it combines two types of insulin in one injection.
 
(Click Humalog Mix75/25 Uses for more information, including possible off-label uses.)
 

Who Makes It?

Humalog Mix75/25 is made by Eli Lilly and Company.
 

How Does Humalog Mix75/25 Work?

Insulin is a hormone that is naturally produced by the pancreas. This hormone is important for several functions, such as controlling blood sugar. Insulin helps the cells of your body remove glucose ("sugar") from your bloodstream. This sugar fuels your body's cells, giving them the energy they need to work properly. You may need to take insulin if your pancreas has trouble making enough, which is the case for people with type 1 diabetes and for some people who have type 2 diabetes.
 
Humalog Mix75/25 contains two different insulins -- one that is rapid-acting (insulin lispro) and one that is intermediate-acting (insulin lispro protamine). It starts working quickly and continues to work for several hours.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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