Endocrine System Home > What Is Canagliflozin Used For?
Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. Normally, the kidneys filter glucose (sugar) out of the blood and into the urine. However, SGLT transporters help this glucose to be reabsorbed back into the blood in the kidneys. Essentially, the kidneys filter out and then "reclaim" the glucose.
Canagliflozin inhibits one of the types of these transporters, preventing the kidneys from reabsorbing the glucose. This leads to glucose loss through the urine.
This drug is not approved for use in children (defined as individuals younger than 18 years old). Talk with your child's healthcare provider about the benefits and risks of using canagliflozin in children.