Endocrine System Home > What Is Canagliflozin Used For?

How Does Canagliflozin Work?

Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. Normally, the kidneys filter glucose (sugar) out of the blood and into the urine. However, SGLT transporters help this glucose to be reabsorbed back into the blood in the kidneys. Essentially, the kidneys filter out and then "reclaim" the glucose.
 
Canagliflozin inhibits one of the types of these transporters, preventing the kidneys from reabsorbing the glucose. This leads to glucose loss through the urine.
 

Can Children Use It?

This drug is not approved for use in children (defined as individuals younger than 18 years old). Talk with your child's healthcare provider about the benefits and risks of using canagliflozin in children.
 

What About Off-Label Uses?

On occasion, your healthcare provider may recommend this medication for treating something other than type 2 diabetes. This is called an "off-label" use. At this time, there are no well-accepted off-label uses for canagliflozin.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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