Endocrine System Home > Alogliptin and Pioglitazone

Healthcare providers may recommend treatment with alogliptin and pioglitazone in people with type 2 diabetes. The combination medication works by lowering the amount of sugar produced by the liver and by increasing the amount of insulin produced in response to meals. It comes in tablet form and is taken once daily. Side effects may include a runny nose, back pain, and upper respiratory tract infections.

 

What Is Alogliptin and Pioglitazone?

Alogliptin and pioglitazone (Oseni®) is a prescription medication approved to treat adults with type 2 diabetes. It is used in conjunction with an appropriate diet and exercise to improve blood glucose (blood sugar) control. Alogliptin and pioglitazone contains a combination of two diabetes medications: alogliptin (Nesina®) and pioglitazone (Actos®).
 
Alogliptin and pioglitazone will not work to treat type 1 diabetes or diabetic ketoacidosis, a potentially life-threatening problem that can occur in people with diabetes. It should not be used in people with these conditions.
 
(Click What Is Alogliptin and Pioglitazone Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

As with any medicine, alogliptin and pioglitazone can cause side effects. However, not everyone who takes the drug will experience problems. Most people tolerate it quite well.
 
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
 
Common side effects seen with alogliptin and pioglitazone include but are not limited to:
   
(Click Alogliptin and Pioglitazone Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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