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Side Effects of Liraglutide

Common Side Effects

Liraglutide has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking liraglutide (alone or in combination with other diabetes medications) were documented and compared to those that occurred in a similar group of people taking other diabetes medications (without liraglutide).
This way, it is possible to see what side effects occurred, how often they appeared, and how they compared to the groups taking other diabetes medications.
The following percentages come from the studies in which people took liraglutide only (not in combination with other diabetes medications), as these numbers probably most fairly represent the actual likelihood of liraglutide causing these adverse reactions. In other words, the results are not skewed by the simultaneous use of other diabetes medications.
In these studies, the most common liraglutide side effects included:
  • Nausea -- in up to 28.4 percent of people
  • Diarrhea -- up to 17.1 percent
  • Vomiting -- up to 10.9 percent
  • Constipation -- up to 9.9 percent
  • Upper respiratory tract infection (such as the common cold) -- up to 9.5 percent.
Other, slightly less common side effects (occurring in 5 to 7.4 percent of people) in such studies included:
Gastrointestinal problems (particularly nausea, diarrhea, or vomiting) usually are most common when people first start taking liraglutide and generally improve gradually with time. Also, such problems are more common with a higher liraglutide dosage.
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