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What Is Linagliptin Used For?

How Does This Medicine Work?

Linagliptin is part of a class of diabetes medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 is an enzyme that breaks down incretin hormones. As a DPP-4 inhibitor, linagliptin slows down the breakdown of incretin hormones, increasing the level of these hormones in the body. It is this increase in incretin hormones that is responsible for the beneficial actions of linagliptin, such as increasing insulin production in response to meals and decreasing the amount of glucose (sugar) that the liver produces.
Because incretin hormones are more active in response to higher blood sugar levels, the risk of dangerously low blood sugar levels (hypoglycemia) is low with linagliptin.

Is It Safe for Children to Take Linagliptin?

Linagliptin is not approved for use in children. Talk with your child's healthcare provider about the benefits and risks of using this medicine in children.

Is Linagliptin Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this medicine for treating something other than type 2 diabetes, or using it in a way that is different from its approved method of use. This would be known as an "off-label" use. At this time, there are no well-accepted off-label uses for linagliptin.
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Linagliptin Drug Information

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