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Drug Interactions With Linagliptin

Taking certain medications with linagliptin may result in potentially serious interactions. Some of these complications can increase your risk for side effects, such as low blood sugar levels, or decrease the effectiveness of linagliptin. Sulfonylurea medications, CYP 3A4 inducers, and P-glycoprotein inducers are among the products that can lead to negative reactions when taken with linagliptin.

An Overview of Linagliptin Interactions

Linagliptin (Tradjenta™) may react with a number of other medications. Some of the drugs that may lead to interactions with linagliptin include but are not limited to:
  • CYP 3A4 inducer medications, such as:


  • Insulin secretagogues or insulin, such as:
    • Insulin of any type
    • Meglitinides, such as:
    • Sulfonylureas (or sulfonylurea combination medications), such as:
  • P-glycoprotein inducers, such as:


Healthy Eating for People With Diabetes

Linagliptin Drug Information

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