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Korlym Warnings and Precautions

People who plan to take Korlym should know that this drug may increase the risk for dangerous complications, including adrenal insufficiency, heart rhythm problems, and other medical issues. Safety precautions for taking Korlym also include specific warnings for women who are pregnant, as this drug can harm a fetus. Other complications include drug interactions and allergic reactions.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Korlym™ (mifepristone) if you have:
  • Liver disease, such as cirrhosis, liver failure, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Been taking medicines known as corticosteroids for other serious medical problems
  • Had an organ transplant
  • Bleeding problems
  • Unexplained vaginal bleeding
  • Cancer of the lining of the uterus (endometrial cancer)
  • Overgrowth or thickening of the lining of the uterus (endometrial hyperplasia)
  • Low levels of potassium in your blood
  • An irregular heart rhythm (arrhythmia) called QT prolongation
  • Heart disease
  • Thyroid problems, such as an underactive or overactive thyroid (hypothyroidism or hyperthyroidism)
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
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Korlym Drug Information

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