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Korlym Uses

How Does It Work?

Korlym is a cortisol receptor blocker. It works by preventing cortisol from binding to its receptor. This reduces the effects of cortisol, such as high blood sugar. However, Korlym does not decrease cortisol production by the body.

Can Children Use Korlym?

Korlym has not been studied in children and is not approved for use in this age group (usually considered individuals younger than 18 years old). Talk to your child's healthcare provider about the risks and benefits of using this medicine in children.

Can Older Adults Use It?

Older adults can use Korlym. However, the medicine has not been adequately studied in older adults. Therefore, older adults who take this medicine may need to be monitored more closely.

Are There Off-Label Korlym Uses?

On occasion, a healthcare provider may recommend Korlym for treating something other than the conditions discussed in this article. This is called an "off-label" use. At this time, there are no well-accepted off-label uses for Korlym.
However, the drug is currently being studied for the treatment of psychotic depression, a serious type of depression in which a person loses touch with reality (has psychosis). Mifeprex®, a different medication that contains the same active ingredient (mifepristone), is approved to terminate an early pregnancy (to cause an abortion), but Korlym is not approved for this use; this would be an off-label use.
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Korlym Drug Information

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